FOLVINE

Composition – Folic Acid 5 mg

Dosage Form – Tablet

Folate and folic acid are forms of vitamin B9 used for deficiency and to prevent pregnancy complications. Many foods contain folate or have folic acid added.
Folic acid is used for preventing and treating low blood levels of folate (folate deficiency) and high blood levels of homocysteine (hyperhomocysteinemia). People who are pregnant or might become pregnant take folic acid to prevent serious birth defects such as spina bifida.

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Product Information

Folic acid is also used for many other conditions including depression, stroke, decline in memory and thinking skills, and many others.

Uses

Effective for folate deficiency. Taking folic acid improves folate deficiency.

Side Effects

It is likely safe for most people to take folic acid in doses of no more than 1 mg daily. Doses higher than 1 mg daily may be unsafe. These doses might cause stomach upset, nausea, diarrhea, irritability, confusion, behavior changes, skin reactions, seizures, and other side effects.

How to Use

As prescribed by physician

How it Works

Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase (DHFR). These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate tRNA, and generate and use formate. Using vitamin B12 as a cofactor, folic acid can normalize high homocysteine levels by remethylation of homocysteine to methionine via methionine synthetase.

Fact Box

Interactions with Drugs

  • "1. Folic acid may decrease the excretion rate of Abacavir which could result in a higher serum level.
  • 2. Abemaciclib may decrease the excretion rate of Folic acid which could result in a higher serum level.
  • 3. Aceclofenac may decrease the excretion rate of Folic acid which could result in a higher serum level.
  • 4. Acemetacin may decrease the excretion rate of Folic acid which could result in a higher serum level.

Quick Tips

"Folic Acid is used for the treatment of folic acid deficiency.
It is also taken before and during pregnancy to decrease the risk of defects in the neural tube, which forms the spinal cord in the baby.
Inform your doctor if you have a history of seizures as you may need a higher dose of the seizure medicines than what you normally take."

What if you forgot to take

If you have missed giving any dose of this medicine, then give it as soon as you remember. If it's already time for the next dose then skip the missed dose and follow the regular dosing schedule. Follow the dosing schedule regularly & take this medicine at regular intervals.

FAQs

References

"1. Kamen B: Folate and antifolate pharmacology. Semin Oncol. 1997 Oct;24(5 Suppl 18):S18-30-S18-39. [Article]
2. Fenech M, Aitken C, Rinaldi J: Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults. Carcinogenesis. 1998 Jul;19(7):1163-71. [Article]
3. Zittoun J: [Anemias due to disorder of folate, vitamin B12 and transcobalamin metabolism]. Rev Prat. 1993 Jun 1;43(11):1358-63. [Article]
4. Alaimo K, McDowell MA, Briefel RR, Bischof AM, Caughman CR, Loria CM, Johnson CL: Dietary intake of vitamins, minerals, and fiber of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1, 1988-91. Adv Data. 1994 Nov 14;(258):1-28.

Dosage Form

Tablet